December 31, 2021

Oncolytic Viral Therapy Engenders a Clinical Response in a Recurrent Ovarian Cancer Patient

Abstract Platinum-resistant ovarian cancer frequently develops in response to multiple lines of chemotherapy, whereupon the disease becomes relatively intractable and clinical recourse is limited. We document a 58-year-old, advanced-stage, platinum-resistant ovarian cancer patient who previously failed numerous cytotoxic and targeted therapy regimens. She was referred to our gynecologic oncology service with a CA-125 of 3194 …

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Hormone Therapy and the Risk for Breast Cancer: Where Are We Now?

Abstract Purpose: To review the long-term data associated with taking hormone replacement therapy (HRT) and the controversial outcomes. Data sources: A literature review was conducted via Pub Med. The relevant search terms included hormone replacement therapy, breast cancer, cancer mortality, and health risks. The accessed publications were in English and not limited by publication date. …

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Robotic-Assisted Surgery for the Treatment of Breast and Cervical Cancers: Where is the Consensus?

Introduction In 1983, the first surgical robot was introduced, a device that ultimately incorporated the development of robotic arms to complement ophthalmologic procedures [1]. The Zeus® system was initially utilized in gynecologic surgery to reconnect fallopian tubes in 1997 [2] and in 2000, the da Vinci Surgery System became the first robotic surgery system approved …

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Talc Powder and Ovarian Cancer: Piercing the Cloud of Controversy

Abstract Talc, a desiccant, has been historically used as baby powder by numerous women to enhance their feminine hygiene. However, since talc is frequently identified in proximity to asbestos, studies have implicated the role of talc use in effectuating carcinogenesis, particularly ovarian cancer. While retrospective studies have reported on the association of genital powder and …

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Metformin in Ovarian Cancer

A Phase II, Open-Label, Non-Randomized, Prospective Study Assessing Paclitaxel, Carboplatin and Metformin in the Treatment of Advanced Stage Ovarian Carcinoma ABSTRACT Objectives. The purpose of this study was to assess the efficacy and tolerability of a paclitaxel, carboplatin and metformin regimen in the first line treatment of advanced stage ovarian, fallopian tube, and primary peritoneal …

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